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Non-invasive assessment of arterial stiffness through pulse wave velocity PWV analysis is becoming common clinical practice. However, the effects of measurement noise, temporal resolution and similarity of the two waveforms used for PWV calculation upon accuracy and variability are unknown. We studied these effects upon PWV estimates given by foot-to-foot, least squared difference, and cross-correlation algorithms. We assessed accuracy using numerically generated blood pressure and flow waveforms for which the theoretical PWV was known to compare with the algorithm estimates. We assessed variability using clinical measurements in 28 human subjects. Wave shape similarity was quantified using a cross correlation-coefficient CC Coefficient , which decreases with increasing distance between waveform measurements sites. Based on our results, we propose the following criteria to identify the most accurate and least variable algorithm given the noise, resolution and CC Coefficient of the measured waveforms.

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The control valve 18 has a differential piston 23 controlling an inlet valve 21 for pressure from a dual brake valve 12, and an outlet valve 22 for exhaust. The smaller piston area is acted upon by the brake valve pressure, the larger area by the regulated front wheel brake pressure, and the differential area by pressure from a change over valve 27 which supplies either the regulated rear wheel brake pressure, if it is above the predetermined value, or the brake valve pressure for the front brakes if there is a pressure failure in the rear circuit.

The change over valve 27 is actuated for the former pressure transmission against a spring by either a piston 31, as shown, or by a pressure actuated switch controlling a solenoid not shown. DE DEB2 en Dual-circuit braking system for vehicles, particularly for trucks, buses and. USA en. DEB2 en. FRB1 en. GBA en. ITB en. SEB en.

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The meeting will be held, in the first day, in the auditorium of the European Union delegation in Japan Minami-Azabu, Minato-ku, Tokyo Further information on this event and the registration page are available here. The next steps on the way to a detailed technical design study need to be planned. The number of participants will be limited to a maximum of 60 people due to space constraints.

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A Technical Assessment of Pulse Wave Velocity Algorithms Applied to Non-invasive Arterial Waveforms

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